The Orbison family moved to Forth Worth sometime in 1942. In Forth Worth, they found employment in the munitions and aircraft factories that had been expanded due to America's entry into World War II. But due to epidemic polio in 1944, Roy and his elder brother Grady were sent back to live with their maternal grandmother, a divorcee, in Vernon. Roy Orbison wrote his first song "A Vow of Love", in front of his grandmother's house the same year. In 1945 he entered and won a contest on KVWC in Vernon and this led to his own radio show singing the same songs every Saturday. In 1946 a medicine show came to town and Roy entered the talent contest singing "Mountain Dew" and "Jole Blon", and tied for first place with a 15-year-old kid. The total prize was $15, so he got $7.50 and gave his buddy half of that for carrying his guitar.

When the War was over, the family re-united in Vernon and soon moved out west to Wink, Texas, in late 1946. He formed his first band when he was thirteen, in 1949. They called themselves The Wink Westerners.